Thrombosis
Find out everything you need to know about thromboses, especially leg vein thromboses, at VenaZiel Berlin MVZ. This article deals with the development, risk factors and symptoms of thrombosis as well as the connection to varicose veins. We also present the latest diagnostic and treatment methods such as VenaSeal and minimally invasive procedures. Find out how you can prevent thrombosis and varicose veins and which aftercare measures are important to maintain your vein health.

Medically tested by:
Dr. Hamidreza Mahoozi, FEBTS, FCCP
First publication:
July 7, 2024
Updated:
January 30, 2025
The VenaZiel Vein Competence Center (VKZ) Berlin has set itself the task of providing patients with comprehensive information about vein diseases and offering them state-of-the-art treatment methods. Thrombosis, especially leg vein thrombosis, is a common and serious condition. In this article, you will learn everything you need to know about the development, risk factors, the different types of thrombosis and the link between varicose veins and leg vein thrombosis.
What is thrombosis?
Thrombosis refers to the formation of a blood clot (thrombus) in a blood vessel, which leads to a narrowing or complete blockage of the vessel. Thromboses can occur in arteries or veins, whereby the latter are referred to as venous thromboses. In rare cases, thrombosis can occur in the arm after a blood sample has been taken, especially if the veins have been injured. A common form of venous thrombosis is leg vein thrombosis, in which a blood clot forms in the deep veins of the legs.
Classification of thromboses
Thromboses are divided into different categories depending on the vessel affected:
Deep vein thrombosis (DVT): This thrombosis occurs in the deep veins of the legs or pelvis. A thrombosis in the thigh can lead to severe swelling and pain, which requires medical clarification. DVTs are particularly dangerous as the clot can dislodge and cause a pulmonary embolism.
Superficial vein thrombosis (SVT): This thrombosis affects the superficial veins and is often associated with varicose veins. Although less dangerous than DVTs, they can be painful and lead to complications.
Arterial thrombosis: This occurs in the arteries and can lead to serious complications such as heart attack or stroke. However, it is less common than venous thrombosis.
Causes and risk factors for leg vein thrombosis
The development of leg vein thrombosis can be favored by various factors, including
- Lack of exercise: Prolonged immobility, for example being bedridden or sitting for long periods (e.g. on long-haul flights), increases the risk of thrombosis.
- Genetic predisposition: A family history of thrombosis may indicate a genetic predisposition.
- Hormonal influences: Taking hormone preparations, such as the contraceptive pill or hormone replacement therapy, can increase the risk of thrombosis.
- Diseases and operations: Certain diseases such as cancer or operations can increase the risk of thrombosis.
- Age and obesity: The risk of thrombosis increases with age and obesity.
Symptoms of leg vein thrombosis
The symptoms of leg vein thrombosis can vary, but the following signs are frequently observed:
- Swelling of the affected leg
- Sensitivity to pain, often in the calf
- Redness or bluish discoloration of the skin
- Overheating of the affected area
- Feeling of tension in the leg
Typical symptoms of thrombosis in the thigh include swelling, pain, redness and a feeling of tightness.
It is important to take these symptoms seriously and seek medical advice immediately if you suspect a thrombosis. In the early stages of thrombosis, symptoms such as swelling, redness or a feeling of tightness in the affected leg may occur.
The link between varicose veins and leg vein thrombosis
Varicose veins are dilated, tortuous veins that mainly occur in the legs.
They are caused by a weakness of the vein walls and valves, which leads to a backflow of blood and congestion in the veins.
This chronic venous weakness favors the formation of blood clots and thus increases the risk of leg vein thrombosis.
How do varicose veins develop?
Varicose veins are caused by a combination of genetic predisposition and external factors.
The main causes include
- Genetic predisposition: A family history of varicose veins indicates a congenital weakness of the connective tissue.
- Hormonal influences: Hormonal changes, especially during pregnancy, can promote the development of varicose veins.
- Lack of exercise and prolonged standing: Standing or sitting without sufficient movement promotes the development of varicose veins.
- Overweight: Excessive body weight increases the pressure on the leg veins and can lead to the formation of varicose veins.
The risk of varicose veins and their connection with thrombosis
Varicose veins can increase the risk of thrombosis for several reasons:
- Blood congestion: Insufficient functioning of the venous valves causes blood to back up in the legs, which encourages the formation of blood clots.
- Inflammatory reactions: Varicose veins can trigger inflammatory processes in the vein walls, which increase the risk of thrombosis.
- Changes in blood clotting: Patients with varicose veins may experience changes in blood clotting that promote thrombosis.

Diagnostics and treatment at the VenaZiel Vein Competence Center (VKZ) Berlin
At the VenaZiel Vein Competence Center (VKZ) Berlin, we offer state-of-the-art diagnostics and treatment options for thrombosis and varicose veins. Our services include:
- Duplex sonography: An ultrasound examination that provides detailed images of the veins and makes blood clots and vein changes visible.
- D-dimer test: A blood test that detects elevated levels of a certain protein that is released when the blood coagulates.
- Compression therapy: The use of compression stockings to improve blood flow and reduce swelling.
- Drug therapy: The use of blood-thinning medication (anticoagulants) to prevent the spread of thrombosis.
- Minimally invasive procedures: Treatments such as VenaSeal (vein glue), radiofrequency ablation (RFA) and endovenous laser therapy (EVLT) to remove varicose veins without surgery or anesthesia.
VenaSeal (vein adhesive): A gentle treatment method
VenaSeal is a particularly gentle and innovative method for treating varicose veins. A special medical adhesive is injected into the affected vein, which seals the vein. The blood flow is then redirected to healthy veins. The advantages of VenaSeal are
- Minimally invasive: The procedure requires no incisions or anesthesia, which shortens the recovery time.
- Rapid recovery: Patients can usually resume their normal activities immediately after treatment.
- No need for compression stockings: In contrast to other methods, patients generally do not need to wear compression stockings after treatment with VenaSeal.
Prevention of thrombosis and varicose veins
Prevention plays a crucial role in dealing with thrombosis and varicose veins.
The following measures can help:
- Exercise: Regular physical activity promotes blood flow and reduces the risk of blood clots.
- Compression stockings: Wearing compression stockings can improve blood flow in the legs and prevent the development of varicose veins.
- Healthy diet: A balanced diet supports vascular health and helps to prevent obesity.
- Sufficient fluids: Drinking enough keeps the blood thin and prevents the formation of blood clots.
Aftercare and lifestyle changes
After the treatment of thrombosis and varicose veins, careful aftercare is crucial to prevent relapses and maintain the health of the veins.
This includes
- Regular check-ups: Follow-up appointments to monitor the success of the treatment and for early detection of any complications.
- Long-term compression therapy: Depending on the severity of the disease, long-term use of compression stockings may be necessary.
- Lifestyle changes: A healthy diet, regular exercise and avoiding long periods of standing or sitting are important preventative measures.
Conclusion
The link between varicose veins and leg vein thrombosis is an important issue in the field of vein health.
The VenaZiel Vein Competence Center (VKZ) Berlin is at your side with comprehensive expertise and state-of-the-art treatment methods.
If thrombosis is suspected or for the treatment of varicose veins, we offer individual advice and customized therapies.
Do not hesitate to contact us and make an appointment.
Your vein health is important to us.